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Targeted inhibition of histone deacetylase leads to suppression of Ewing sarcoma tumor growth through an unappreciated EWS-FLI1/HDAC3/HSP90 signaling axis

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Year: 2019
Type: article
Source: Journal of Molecular Medicine
DOI: 10.1007/s00109-019-01782-0
Authors: Yan Ma, Michael Baltezor, Lian Rajewski, Jennifer Crow, Glenson Samuel, Vincent S. Staggs, Katherine M. Chastain, Jeffrey A. Toretsky, Scott J. Weir, Andrew K. Godwin
Institutions: University of Kansas Medical Center, University of Kansas, The University of Kansas Cancer Center, Children's Mercy Hospital, University of Missouri–Kansas City, Georgetown University Medical Center
Language: English

Topic: Sarcoma Diagnosis and Treatment
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
SDG: Good health and well-being

Open Access status: green

Funders: National Cancer Institute, National Institute of General Medical Sciences
Awards: Novel Approaches for the Control of Microbial Pathogens, Integrated exosomes profiling for minimally invasive diagnosis and monitoring of cancer, The Kansas Institute for Precision Medicine, The University of Kansas Cancer Center
OpenAlex ID: W2941585344
FWCI: 3.307
Cites: 49
Cited by: 27
Related to: 10
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