Work

Enhanced Diffusivity in Metal-Organic Frameworks for Use as a Drug Delivery System

Year: 2018
Type: article
Abstract: The pharmaceutical industry is undergoing a transformative shift toward personalized medicine and new methods for controlled delivery of those drugs are necessary. MOFs are an exciting potential sorbent due to their extremely high surface areas (1,000 m^2/g and 10,000 m^2/g) and ultrafine molecular sieving ability. In this project, we designed, constructed, and validated a system and mathematical model for assessing the drug release profiles from porous media. The work culminates with a systematic perspective identifying the need for stable, size-tunable frameworks that could serve as an excellent and effective drug delivery system.
Source: Digital WPI
Authors: Corey Scott, John P Palumbo, Colby Whitcomb, Matthew Bennett
Language: English
Field: Chemistry
Open Access status: green
OpenAlex ID: W2941771799
FWCI:
Cites: 31
Cited by: 1
Related to: 10