Influence of ZnO nanoparticles on Candida albicans isolates biofilm formed on the urinary catheter.
Year: 2018
Type: article
Abstract: BACKGROUND AND OBJECTIVES: adhesion and biofilm formation. MATERIALS AND METHODS: by common phenotypic and genotyping methods. ZnO nanoparticles with 30 nm were made by the sol-gel method, which was confirmed by XRD (X-ray diffraction) and scanning electron microscope (SEM) methods. Candidal adhesion and biofilm assays were performed on catheter surfaces for 2 and 48 hours, respectively. The effect of sub-MIC (minimum inhibitory concentrations) and MIC concentrations of ZnO-np on biofilm formation was evaluated after 24 hours using Crystal violet (CV), colony-forming unit (CFU), and SEM. RESULTS: biofilm biomass compared to susceptible isolates. CONCLUSION: Zno-np exhibits inhibitory effects on biofilms of both isolates. These findings provide an important advantage of ZnO that may be useful in the treatment of catheter-related urinary tract infection.
Source: Europe PMC (PubMed Central)
Authors: Seyedeh Sedigheh Hosseini, Ezzatollah Ghaemi, Faramarz Koohsar
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2942376834