Year: 2015
Type: article
Study design: Observational Study
Abstract: Objective: To evaluate perinatal risk factors and parental characteristics in Autistic Spectrum Disorder (ASD). Method: Obstetric conditions and parental characteristics were compared between ASD and two control groups without ASD (one from emergency room and the other from psychiatry outpatient service and daycare hospital). Result: There were 20 patients in each group (17 boys and 3 girls), ages 6-18. The pervasive developmental disorder (PDD) case group had 4 Autistic, 11 Asperger´s and 5 pervasive developmental disorder not otherwise specified (PDD-NOS). Assisted pregnancies in 20% of PDD case group and 5% of control group B. All control group A were spontaneous pregnancies (p= 0.039). Statistically significant differences in maternal diseases between PDD case and control group A (p=0.041). Delivered by cesarean section in 65% of PDD case group, against 35% control A group and 25% of control B group (p=0.039). Statistically significant differences in family and maternal psychiatry history between three groups (p=0.008 and p=0.001). ASD has been diagnosed in 30% of relatives in PDD case group and none in control groups (p=0.01). Conclusion: This study found some obstetric and parental risk factors related with ASD, according to the literature. Future research should attempt to identify obstetric factors and understand their relationship with different genetically influenced processes in early development.
Institution: Hospital Clínico Universitario de Valladolid
Language: Spanish
Subfield: Cognitive Neuroscience
Field: Neuroscience
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W2943112913