Work

Examinations of DRD4, DRD5 and SNAP-25 as candidate genes in Attention Deficit Hyperactivity Disorder

Year: 2005

Type: dissertation

Abstract: Attention deficit hyperactivity disorder (ADHD) is a common early onset childhood\ndisorder. Symptoms o f the disorder include inattentiveness, impulsiveness,\ndistractibility and hyperactivity. Family, twin and adoption studies have estimated the\nheritability of ADHD to be 70-90% and it is believed that this genetic contribution to\nthe disorder takes the form of multiple susceptibility genes of small individual effect.\nThe dopaminergic neurotransmitter system has been implicated in the aetiology of\nADHD by animal, pharmacological, neuroimaging and molecular studies and a\nnumber of susceptibility genes for the disorder have been identified. The aim of this\nthesis was to explore the molecular genetics of ADHD in relation to three\ndopaminergic related genes (DRD4, DRD5 and SNAP-25) using a sample of DSM IV\ndiagnosed ADHD probands and their parents.

Source: Arrow@dit (Dublin Institute of Technology)

Author: Naomi Lowe

Language: English

Topic: Attention Deficit Hyperactivity Disorder

Subfield: Psychiatry and Mental health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2943464357

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