Work

The role of gut microbiota in non-alcoholic fatty liver disease: pathways of mechanisms

Year: 2019

Type: article

Abstract: Nonalcoholic fatty liver disease (NAFLD) is a hepatic manifestation of metabolic syndrome. Its prevalence increases with increasing rates of obesity, insulin resistance, and diabetes mellitus. The pathogenesis of NAFLD involves many factors, including the gastrointestinal microbiota. However, there is still debate about the impact of gut dysbiosis in the NAFLD disease progression. Therefore, this paper aims to review the relationship between gut microbiota and other risk factors for NAFLD and how gut dysbiosis plays a role in the pathogenesis of NAFLD. Hopefully, this paper can make an appropriate contribution to the development of NAFLD research in the future.

Source: Bioscience of Microbiota Food and Health

DOI: 10.12938/bmfh.18-032

Authors: Chyntia Olivia Maurine JASIRWAN, Cosmas Rinaldi Adithya LESMANA, Irsan HASAN, Andri Sanityosos SULAIMAN, Rino Alvani GANI

Institutions: University of Indonesia, Rumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo

Language: English

Topic: Gut microbiota and health

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W2944460908

FWCI: 2.65

Cites: 64

Cited by: 106

Related to: 10