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Diverse compounds from pleuromutilin lead to a thioredoxin inhibitor and inducer of ferroptosis

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Year: 2019
Type: article
Source: Nature Chemistry
DOI: 10.1038/s41557-019-0261-6
Authors: Evijola Llabani, Robert W. Hicklin, Hyang Yeon Lee, Stephen E. Motika, Lisa A. Crawford, Eranthie Weerapana, Paul J. Hergenrother
Institutions: University of Illinois Urbana-Champaign, Boston College
Language: English

Topic: Ferroptosis and cancer prognosis
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, University of Illinois at Urbana-Champaign, National Institute of General Medical Sciences
Awards: Defining Parameters for Compound Accumulation in Gram-Negative Pathogens, Training Program at the Chemistry Biology Interface
OpenAlex ID: W2945478689
FWCI: 21.84
Cites: 63
Cited by: 234
Related to: 10
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