Work

A novel RAS internal tandem duplication involving the switch II domain disrupts GAP-binding and activates oncogenic signaling.

Year: 2019

Type: conference-abstract

Source: Journal of Clinical Oncology

DOI: 10.1200/jco.2019.37.15_suppl.e15069

Authors: Emil Lou, Thomas Turbyville, Dhirendra Simanshu, Rendong Yang, John Columbus, Bob Stephens, Drew Sciacca, Anne Sarver, Subbaya Subramanian, Dwight Nissley, Andrew Nelson

Institutions: University of Minnesota, National Institutes of Health, Frederick National Laboratory for Cancer Research

Language: English

Topic: Protein Kinase Regulation and GTPase Signaling

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W2947454795

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