Year: 2019
Type: article
Abstract: The national burden of cardiovascular disease (CVD) continues to impose significant risk of morbidity, mortality and increased costs. While traditional risk factors have been well-established, the evolving role of non-traditional risk factors, including socioeconomic and psychosocial factors, is increasingly being recognized. Several studies have acknowledged an association between marital status and the presence of CVD and its associated adverse outcomes. Across multiple U.S. and international cohorts, patients who are unmarried, including those who are divorced, separated, widowed, or never married, have an increased rate of adverse cardiovascular events when compared to their married counterparts. Some studies suggest that marriage may have a more protective role for men compared to women. Furthermore, dissatisfaction in a marriage and marriage quality have significant impact on cardiovascular risk. Psychosocial and socioeconomic factors, as well as other acute stressors, may contribute to the association between marital status and CVD outcomes, but the underlying mechanisms are not completely clear. Further investigation is required to identify potential targets for intervention and to determine whether more aggressive targeting of standard anti-atherosclerotic therapies can favorably impact CVD risk in unmarried patients.
Institutions: Emory University, Northwestern University
Language: English
Subfield: Demography
Field: Social Sciences
Domain: Social Sciences
Open Access status: hybrid
Estimated APC paid: $2,850
Awards: Mental Stress Ischemia: Prognosis and Genetic Influences, Metabolomics of subclinical and clinical cardiovascular disease, G456172418, Cell therapy for diabetic peripheral neurovascular complications, Heart Failure Clinical Trials Network, Injury and Repair Factors Promoting Atherosclerosis in HIV, The role of the renin-angiotensin-endothelial pathway in AD, Serious Hazards of Transfusion & Cellular Therapies: Mechanisms and Intervention, Genome-wide association study of MI in Caucasians, G9000154236, G9000162727, G9000265748, G9000352489
OpenAlex ID: W2947687531
