Work

Modular, tissue-specific, and biodegradable hydrogel cross-linkers for tissue engineering

Year: 2019

Type: article

Abstract: -isopropylacrylamide) to produce rapidly cross-linking, highly swollen, cytocompatible, and hydrolytically degradable hydrogels suitable for mesenchymal stem cell encapsulation. These favorable properties, combined with PdBT's modular design and ease of functionalization, establish strong potential for its usage in tissue engineering applications.

Source: Science Advances

DOI: 10.1126/sciadv.aaw7396

Authors: J. L. Guo, Y. S. Kim, V. Y. Xie, B. T. Smith, E. Watson, J. Lam, H. A. Pearce, P. S. Engel, A. G. Mikos

Institutions: Rice University, Center for Biologics Evaluation and Research, United States Food and Drug Administration

Language: English

Topic: Hydrogels: synthesis, properties, applications

Subfield: Molecular Medicine

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $4,500

Funders: National Institutes of Health, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institute of Biomedical Imaging and Bioengineering, National Institute of Dental and Craniofacial Research

Awards: Center for Engineering Complex Tissues, Rapidly-Degrading Calcium Phosphate Cements for Orthopedic Tissue Engineering., "A Two-Stage High-Fidelity, Anti-Infective Approach to Craniofacial Repair in Novel Ovine Model", G872398379, G9000336701

OpenAlex ID: W2948201679

FWCI: 5.371

Cites: 44

Cited by: 108

Related to: 10