Work

Intracranial Pressure and Intracranial Elastance Monitoring in Neurocritical Care

Year: 2019

Type: review

Abstract: Patients with acute brain injuries tend to be physiologically unstable and at risk of rapid and potentially life-threatening decompensation due to shifts in intracranial compartment volumes and consequent intracranial hypertension. Invasive intracranial pressure (ICP) monitoring therefore remains a cornerstone of modern neurocritical care, despite the attendant risks of infection and damage to brain tissue arising from the surgical placement of a catheter or pressure transducer into the cerebrospinal fluid or brain tissue compartments. In addition to ICP monitoring, tracking of the intracranial capacity to buffer shifts in compartment volumes would help in the assessment of patient state, inform clinical decision making, and guide therapeutic interventions. We review the anatomy, physiology, and current technology relevant to clinical management of patients with acute brain injury and outline unmet clinical needs to advance patient monitoring in neurocritical care.

Source: Annual Review of Biomedical Engineering

DOI: 10.1146/annurev-bioeng-060418-052257

Authors: Thomas Heldt, Tommaso Zoerle, Daniel Teichmann, Nino Stocchetti

Institutions: Massachusetts Institute of Technology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, University of Milan

Language: English

Topic: Traumatic Brain Injury and Neurovascular Disturbances

Subfield: Clinical Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funder: Deutsche Forschungsgemeinschaft