Work

The structure-activity profile of mercaptobenzamides’ anti-HIV activity suggests that thermodynamics of metabolism is more important than binding affinity to the target

Year: 2019

Type: article

Source: European Journal of Medicinal Chemistry

DOI: 10.1016/j.ejmech.2019.06.020

Authors: Herman Nikolayevskiy, Marco Robello, Michael T. Scerba, Evan H. Pasternak, Mrinmoy Saha, Tracy L. Hartman, Caitlin A. Buchholz, Robert W. Buckheit, Stewart R. Durell, Daniel H. Appella

Institutions: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, ImQuest BioSciences (United States), National Cancer Institute

Language: English

Topic: HIV/AIDS drug development and treatment

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Cancer Institute, National Institute of Diabetes and Digestive and Kidney Diseases, Office of AIDS Research

Awards: HIV NCp7 inhibitors and Multivalent Inhibition of Membrane Receptors, G9000107583

OpenAlex ID: W2948887983

FWCI: 0.857

Cites: 39

Cited by: 8

Related to: 10