Work

Synthesis of an α-phosphono-α,α-difluoroacetamide analogue of the diphosphoinositol pentakisphosphate 5-InsP 7

Year: 2019

Type: article

Abstract: A synthetic, fluorinated analogue of 5-InsP 7 binds to the kinase domain of PPIP5K2, suggesting new strategies for designing diphosphoinositol phosphate mimics.

Source: MedChemComm

DOI: 10.1039/c9md00163h

Authors: Andrew M. Riley, Huanchen Wang, Stephen B. Shears, Barry V. L. Potter

Institutions: University of Oxford, National Institutes of Health, National Institute of Environmental Health Sciences

Language: English

Topic: Organophosphorus compounds synthesis

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $1,990

Funders: Wellcome Trust, National Institute of Environmental Health Sciences

Award: Chemical Biology of Cellular Signalling using Polyphosphate Messengers.

OpenAlex ID: W2948910587

FWCI: 0.686

Cites: 34

Cited by: 15

Related to: 10