Work

5-Arylthio Substituted 2-Amino-4-oxo-6-methylpyrrolo[2,3-d]pyrimidine Antifolates as Thymidylate Synthase Inhibitors and Antitumor Agents

Year: 1995

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/jm00022a015

Authors: Aleem Gangjee, Rajesh Devraj, John J. McGuire, Roy L. Kisliuk

Institution: Duquesne University

Language: English

Topic: Heterocyclic Compound Synthesis and Bioactivity

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Institutes of Health, National Cancer Institute, National Institute of General Medical Sciences, National Institute of Allergy and Infectious Diseases

Awards: FOLYLPOLYGLUTAMATE SYNTHETASE IN CANCER CHEMOTHERAPY, SYNTHESIS OF RIGID ANALOGS RELATED TO TRIMETREXATE, TRICYCLIC ANALOGUES OF TRIMETREXATE AND PIRITREXIM

OpenAlex ID: W2949113139

FWCI: 1.466

Cites:

Cited by: 37

Related to: 10