Work

Germline de novo mutation clusters arise during oocyte aging in genomic regions with high double-strand-break incidence

Year: 2018

Type: article

Study design: Observational Study

Source: Nature Genetics

DOI: 10.1038/s41588-018-0071-6

Authors: Jakob M. Goldmann, Vladimir B. Seplyarskiy, Wendy S. W. Wong, Thierry Vilboux, Pieter B. Neerincx, Dale L. Bodian, Benjamin D. Solomon, Joris A. Veltman, John F. Deeken, Christian Gilissen, John E. Niederhuber

Institutions: Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, Brigham and Women's Hospital, Russian Academy of Sciences, Harvard University, Institute for Information Transmission Problems, Inova Health System, University Medical Center Groningen, University of Groningen, Virginia Commonwealth University, Inova Children's Hospital, Virginia Commonwealth University Medical Center, Centre for Life, Donders Centre for Neuroscience, Newcastle University, Radboud University Nijmegen, Johns Hopkins University

Language: English

Topic: Genomics and Rare Diseases

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Inova Health System, FP7 Ideas: European Research Council

Award: Detection and interpretation of de novo mutations and structural genomic variations in mental retardation

OpenAlex ID: W2949291528

FWCI: 5.364

Cites: 49

Cited by: 89

Related to: 10