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Durable Response of Enzalutamide-resistant Prostate Cancer to Supraphysiological Testosterone Is Associated with a Multifaceted Growth Suppression and Impaired DNA Damage Response Transcriptomic Program in Patient-derived Xenografts

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Year: 2019
Type: article
Source: European Urology
DOI: 10.1016/j.eururo.2019.05.042
Authors: Hung-Ming Lam, Holly M. Nguyen, Mark P. Labrecque, Lisha G. Brown, Ilsa M. Coleman, Roman Gulati, Bryce Lakely, Daniel Sondheim, Payel Chatterjee, Brett T. Marck, Alvin M. Matsumoto, Elahe A. Mostaghel, Michael T. Schweizer, Peter S. Nelson, Eva Corey
Institutions: Macau University of Science and Technology, University of Washington, Fred Hutch Cancer Center, VA Puget Sound Health Care System
Language: English

Topic: Prostate Cancer Treatment and Research
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
SDG: Good health and well-being

Open Access status: green

Funders: Prostate Cancer Foundation, National Institutes of Health, National Cancer Institute
Awards: G1768875591, G1984635589, G302247320, G3181584191, G9000034114, Statistical modeling to support population and translational cancer research, Androgen Receptor Action in Castration Resistant Prostate Cancer, Cancer Center Support Grant, The Pacific Northwest Prostate Cancer SPORE
OpenAlex ID: W2949840574
FWCI: 5.764
Cites: 44
Cited by: 58
Related to: 10
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