Work

CRISPR–Cas9 screens in human cells and primary neurons identify modifiers of C9ORF72 dipeptide-repeat-protein toxicity

Year: 2018

Type: article

Source: Nature Genetics

DOI: 10.1038/s41588-018-0070-7

Authors: Nicholas J. Kramer, Michael S. Haney, David W. Morgens, Ana Jovičić, Julien Couthouis, Amy Li, James Ousey, Rosanna Ma, Gregor Bieri, C. Kimberly Tsui, Yingxiao Shi, Nicholas T. Hertz, Marc Tessier-Lavigne, Justin K. Ichida, Michael C. Bassik, Aaron D. Gitler

Institutions: Stanford Medicine, Stanford University, Genentech, University of Southern California, Broad Center

Language: English

Topic: Amyotrophic Lateral Sclerosis Research

Subfield: Clinical Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Science Foundation, Johns Hopkins University, Target ALS, National Institutes of Health, National Human Genome Research Institute, National Institute of General Medical Sciences, National Institute of Neurological Disorders and Stroke, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Robert Packard Center for ALS Research, Johns Hopkins University

Awards: Validating Secretory Autophagy as a Therapeutic Strategy for Diverse Forms of ALS and FTD, Stanford Neuroscience Research Cores for Gene Vectors, Microscopy, and Behavios, G488457003, Genetics and Developmental Biology Training Program, Accelerating drug development and repurposing using systematic genetic interactio, Innovating Yeast and Human Genetics Approaches to Define Mechanisms of Neurodegenerative Disease, Institutional Training Grant in Genome Science

OpenAlex ID: W2949846456

FWCI: 19.57

Cites: 83

Cited by: 221

Related to: 10