Work

Reactive oxygen species-responsive theranostic nanoparticles for enhanced hypoxic tumor photodynamic therapy via synchronous HIF-1α inhibition and ATP depletion

Year: 2019

Type: article

Abstract: ROS-responsive nanoparticles were designed to co-deliver the small molecule HIF-1α inhibitor Doxy and the photosensitizer IR780 for enhanced PDT efficiency.

Source: Materials Chemistry Frontiers

DOI: 10.1039/c9qm00270g

Authors: Caiyan Zhao, Yunhao Li, Leihou Shao, Xuan Wang, Jianqin Lu, Xianlei Li, Long Chen, Xinyue Cui, Wang Sheng, Xiongwei Deng, Yan Wu

Institutions: Chinese Academy of Sciences, National Center for Nanoscience and Technology, University of Chinese Academy of Sciences, Sun Yat-sen University, Beijing University of Technology

Language: English

Topic: Nanoplatforms for cancer theranostics

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: bronze

Funder: National Natural Science Foundation of China

Awards: G3375896266, G591049518, G7198447024

OpenAlex ID: W2949909029

FWCI: 0.997

Cites: 43

Cited by: 16

Related to: 10