Year: 2014
Type: article
Abstract: Mimulus guttatus and M. nasutus are an evolutionary and ecological model sister species pair differentiated by ecology, mating system, and partial reproductive isolation. Despite extensive research on this system, the history of divergence and differentiation in this sister pair is unclear. We present and analyze a population genomic data set which shows that M. nasutus budded from a central Californian M. guttatus population within the last 200 to 500 thousand years. In this time, the M. nasutus genome has accrued genomic signatures of the transition to predominant selfing, including an elevated proportion of nonsynonymous variants, an accumulation of premature stop codons, and extended levels of linkage disequilibrium. Despite clear biological differentiation, we document genomic signatures of ongoing, bidirectional introgression. We observe a negative relationship between the recombination rate and divergence between M. nasutus and sympatric M. guttatus samples, suggesting that selection acts against M. nasutus ancestry in M. guttatus.
Source: PLoS Genetics
Language: English
Subfield: Genetics
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $3,043
Funders: National Science Foundation, U.S. Department of Energy, Alfred P. Sloan Foundation, University of Georgia, Joint Genome Institute, National Institutes of Health, Office of Science, University of Georgia Research Foundation, Georgia Advanced Computing Resource Center, University of Georgia, National Institute of General Medical Sciences
Awards: Recombination rate variation and evolution in vertebrates, G1286236842, G1414775356, G1765470836, G1816284028, G1863003419, G2397981927, G2409707861, G2539837713, G3083819904, G365575497, G382641700, G4107565357, G419881185, G42916606, G4501827968, G498139845, G5004724115, G5851713598, G6652958823, G7205239661, G805243471, G8291814557, G834277795, Collaborative Research: ABI Innovation: Visualization and Statistics for Spatial Population Genomic Analysis, NSF Postdoctoral Fellowship in Biology FY 2010, G9000016974, G969889393
OpenAlex ID: W2247624088