Genetic and environmental architecture of processing speed across midlife.
Year: 2019
Type: article
Study design: Observational Study
Abstract: OBJECTIVE: Processing Speed (PS) is an important domain in cognitive aging that is characterized by multiple related but nonidentical abilities. Few studies have directly investigated the relationships among PS measures, and none have used genetically informed methods. In this study, we examined the relationship between measures of PS at up to two time points during middle age. METHOD: We examined data from 1,262 middle-aged men when the sample was at a mean age of 56 and a mean age 62 years. Participants completed 6 measures of PS from three different cognitive tests. We used a genetically informative, confirmatory factor analytic approach to evaluate the phenotypic and genetic relationships cross-sectionally at both single time points and across time. RESULTS: ). Cross-time genetic correlations were near unity for all latent factors. CONCLUSION: These results suggest that PS is highly heritable when considered at a latent variable level, and that there are different rates of change in tests of PS within this sample. (PsycINFO Database Record (c) 2019 APA, all rights reserved).
Source: Neuropsychology
DOI: 10.1037/neu0000551
Language: English
Subfield: Experimental and Cognitive Psychology
Field: Psychology
Domain: Social Sciences
Open Access status: hybrid
Funder: National Institute on Aging
OpenAlex ID: W2951007276