Work

No evidence that selection has been less effective at removing deleterious mutations in Europeans than in Africans

Year: 2015

Type: article

Source: Nature Genetics

DOI: 10.1038/ng.3186

Authors: Ron Do, Daniel Balick, Heng Li, Ivan Adzhubei, Shamil Sunyaev, David Reich

Institutions: Broad Institute, Harvard University, Massachusetts Institute of Technology, Brigham and Women's Hospital, Howard Hughes Medical Institute

Language: English

Topic: Evolution and Genetic Dynamics

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Science Foundation, Howard Hughes Medical Institute, National Institutes of Health, Canadian Institutes of Health Research, National Institute of Mental Health, National Human Genome Research Institute, National Institute of General Medical Sciences

Awards: Improving Polygenic Prediction using Next-Generation Data Sets, New methods and enhanced software for predicting functional SNPs, G371884728, Leveraging functional data to predict disease risk in multi-ethnic populations, G543711581, Advanced Tools for Reconstructing Population History, Functional and population genetic architectures of complex disease, A new history and geography of human genes informed by ancient DNA

OpenAlex ID: W2059748199

FWCI: 16.34

Cites: 34

Cited by: 201

Related to: 10