Work

Polycystic ovary syndrome (PCOS) and genetic predisposition: A review article

Year: 2019

Type: review

Abstract: Polycystic ovary syndrome (PCOS) is a heterogeneous condition which is related to an endocrine reproductive disorder of females. It affects females of 18-44 age. The persistent hormonal disbalance leads to the complexities such as numerous cysts, an irregular menstrual cycle that ultimately leads to infertility among females. Many candidate genes have been identified to be one of the causes of PCOS. Different studies have been carried out to find the genetic correlation of PCOS. It is essential to carry out such studies that identify the clear cause of PCOS and its genetic association and hormonal disbalance. This review has highlighted different genes and their correlation with PCOS that leads to hormonal disbalance. Yet not in-depth but an attempt to study the genetic predisposition of PCOS.

Source: European Journal of Obstetrics & Gynecology and Reproductive Biology X

DOI: 10.1016/j.eurox.2019.100060

Authors: Nida Ajmal, Sanam Zeib Khan, Rozeena Shaikh

Institution: Balochistan University of Information Technology, Engineering and Management Sciences

Language: English

Topic: Ovarian function and disorders

Subfield: Reproductive Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,500