Work

Efficacy of Aerosolized Rifaximin versus Tobramycin for Treatment of Pseudomonas aeruginosa Pneumonia in Mice

Year: 2019

Type: article

Abstract: Pseudomonas aeruginosa is a Gram-negative opportunistic bacterial pathogen that can cause chronic lung infections in patients with cystic fibrosis (CF). The current preferred treatment for CF lung infections includes inhaled tobramycin (TOB); however, studies suggest TOB cannot effectively inhibit biofilm formation.

Source: Antimicrobial Agents and Chemotherapy

DOI: 10.1128/aac.02341-18

Authors: Brandon D. Kirby, Roy Al Ahmar, T. Ryan Withers, Meagan E. Valentine, Monica Valentovic, Timothy E. Long, James R. Gaskins, Hongwei D. Yu

Institutions: Marshall University, Cabell Huntington Hospital

Language: English

Topic: Bacterial biofilms and quorum sensing

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: National Institutes of Health, National Institute of General Medical Sciences

Awards: Bioengineering a non-pathogenic bacteria to produce medically-relevant biopolymers, West Virginia IDeA Network of Biomedical Research Excellence (WV-INBRE)

OpenAlex ID: W2951913665

FWCI: 0.414

Cites: 34

Cited by: 8

Related to: 10