Work

Glycosyl 2-Pyridinecarboxylate as an Effective Glycosyl Donor: Glycosidation of Mannose, 2-Azidosugar, and 2-Deoxysugar into Disaccharides.

Year: 1998

Type: article

Abstract: Glycosylation reactions using a glycosyl 2-pyridinecarboxylate as a glycosyl donor were performed. Glycosyl 2-pyridinecarboxylate was designed based on a variation of the Remote Activation Concept and is activated through bidentate coordination to mild Lewis acids such as copper triflate and tin triflate. This method was effective for the glycosidation of not only glucose, but several other sugars such as the mannose-type, 2-azidosugar-type, and 2-deoxysugar-type. Various disaccharides were obtained in excellent yield by this reaction.

Source: Chemical and Pharmaceutical Bulletin

DOI: 10.1248/cpb.46.1244

Authors: Hironori FURUKAWA, Kazunori KOIDE, Ken-ichi TAKAO, Susumu KOBAYASHI

Language: English

Topic: Carbohydrate Chemistry and Synthesis

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: bronze

OpenAlex ID: W2952165918

FWCI: 1.517

Cites:

Cited by: 22

Related to: 10