Work

Treatment of Multidrug-Resistant Vancomycin-Resistant Enterococcus faecium Hardware-Associated Vertebral Osteomyelitis with Oritavancin plus Ampicillin

Year: 2019

Type: article

Abstract: infection associated with hardware. Checkerboard and time-kill assays confirmed synergy between these two antibiotics. Further synergies of oritavancin and ampicillin with rifampin or the endogenous human antimicrobial peptide cathelicidin LL-37 were demonstrated.

Source: Antimicrobial Agents and Chemotherapy

DOI: 10.1128/aac.02622-18

Authors: Samira Dahesh, Brian Wong, Victor Nizet, George Sakoulas, Truc T. Tran, Samuel L. Aitken

Institutions: University of California San Diego, Jerry L. Pettis Memorial VA Medical Center, The University of Texas Health Science Center at Houston, The University of Texas MD Anderson Cancer Center

Language: English

Topic: Antibiotic Resistance in Bacteria

Subfield: Molecular Medicine

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze