Methods for Estimating Resting Energy Expenditure Using Indirect Calorimetry in Adults with Overweight and Obesity (P13-030-19)
Year: 2019
Type: article
Abstract: Standard procedures to estimate resting energy expenditure (REE) using indirect calorimetry are time-consuming, and may be unnecessary. Indeed, the guidelines recommend a pre-test resting period of 30-minutes, followed by a 5-minute stabilization period, and then waiting until the first steady state period (SS), defined as a 5-minute period with a coefficient of variance (CV) of <10% for VO2 and VCO2, to estimate REE. The aim of the study was to evaluate alternative procedures for estimating REE in adults with overweight and obesity. Indirect calorimetry was performed in 37 adults enrolled in a weight loss trial using a metabolic cart (Quark RMR, COSMED). The volume of oxygen (VO2) and volume of carbon dioxide (VCO2) were collected every 10 sec for ≥20-minutes following pre-test resting (10-mins) and stabilization (5-mins) periods. The measurement period was segmented into five-minute (REE6–10, REE11–15, REE16–20, and REE21–25) and rolling (REE6–15, REE6–20, and REE6–25) periods, and VO2, VCO2, and CV were calculated for each period. REE was calculated using standard criteria (REESS). Alternative SS periods of 3- and 4-minutes (REE3 and REE4) were applied to those who did not achieve REESS. REESS estimates were compared to the other estimates of REE using paired t-tests. Participants were 51 ± 14SD yo, primarily women (78%), and had a BMI of 35.4 ± 5.5SD kg/m2. REESS was achieved by 81% (n = 30) of all participants, and 54% (n = 20) achieved REESS during the first 5-minute period (REE6–10) following stabilization. Applying REE3 and REE4 criteria, those who did not reach REESS increased to 92% (n = 34). There were no significant differences between REESS, and REE3 (P = 0.21), REE4 (P = 0.40), REE6–10 (P = 0.38), REE6–15 (P = 0.15) or REE6–20 (P = 0.05). The majority of adults with overweight and obesity met the standard criteria for SS following a reduced pre-test resting period. However, the non-significant difference between REESS and rolling averages suggest the standard criteria may be unnecessary in a group setting. American Heart Association.
Institution: NYU Langone Health
Language: English
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $5,000
OpenAlex ID: W2953249261