Work

The nature of human IL-6

Year: 2019

Type: article

Abstract: Countless functions have been attributed experimentally to IL-6. In this issue of JEM, Spencer et al. (https://doi.org/10.1084/jem.20190344) reveal essential, nonredundant functions of human IL-6. Patients with genetic deficiencies of the IL-6 receptor suffer from “hyper IgE syndrome.”

Source: The Journal of Experimental Medicine

DOI: 10.1084/jem.20191002

Authors: Anne Puel, Jean-Laurent Casanova

Institutions: Hôpital Necker-Enfants Malades, Inserm, Institut des Maladies Génétiques Imagine, Howard Hughes Medical Institute, Rockefeller University

Language: English

Topic: Cytokine Signaling Pathways and Interactions

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funders: Wellcome Trust, Medical Research Council, National Institute of Allergy and Infectious Diseases