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Neratinib inhibits Hippo/YAP signaling, reduces mutant K-RAS expression, and kills pancreatic and blood cancer cells

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Year: 2019
Type: article
Source: Oncogene
DOI: 10.1038/s41388-019-0849-8
Authors: Paul Dent, Laurence Booth, Jane L. Roberts, Junchen Liu, Andrew Poklepovic, Alshad S. Lalani, David Tuveson, Jennifer Martinez, John F. Hancock
Institutions: Virginia Commonwealth University, The University of Texas Health Science Center at Houston, Puma Biotechnology (United States), Cold Spring Harbor Laboratory, National Institute of Environmental Health Sciences
Language: English

Topic: Hippo pathway signaling and YAP/TAZ
Subfield: Cell Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Cancer Institute, National Institute of Environmental Health Sciences
Awards: G1122075389, Pemetrexed and sildenafil for lung cancer, Characterization of the molecular mechanisms of LC3-associated phagocytosis and its role in disease pathogenesis
OpenAlex ID: W2953798516
FWCI: 5.991
Cites: 51
Cited by: 79
Related to: 10
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