Work

Membrane-specific spin trap, 5-dodecylcarbamoyl-5- N -dodecylacetamide-1-pyroline- N -oxide (diC 12 PO): theoretical, bioorthogonal fluorescence imaging and EPR studies

Year: 2019

Type: article

Abstract: PO and DBCO-Rhod demonstrated clear localization of fluorescence with intracellular membranes. These results indicate that targeting of nitrone spin traps to cellular membranes is feasible, and that a bioorthogonal approach can aid the interrogation of their intracellular compartmentalization properties.

Source: Organic & Biomolecular Chemistry

DOI: 10.1039/c9ob01334b

Authors: Colwyn A. Headley, Claire N. Hoffman, Juliana M. Freisen, Yongbin Han, Joseph M. Macklin, Jay L. Zweier, Antal Rockenbauer, Jeff Kuret, Frederick A. Villamena

Institutions: The Ohio State University, Budapest University of Technology and Economics, Institute of Materials and Environmental Chemistry, Hungarian Academy of Sciences

Language: English

Topic: Electron Spin Resonance Studies

Subfield: Biophysics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funders: National Institutes of Health, National Heart, Lung, and Blood Institute, National Institute of General Medical Sciences, National Institute of Biomedical Imaging and Bioengineering

Awards: G1197620297, G1262096520, G1557507746, G2906936810, G3865046396, G5259743537, G9000064536, G9000219089, G9000325033

OpenAlex ID: W2954058366

FWCI: 0.667

Cites: 82

Cited by: 7

Related to: 10