Work

CATACOMB: An endogenous inducible gene that antagonizes H3K27 methylation activity of Polycomb repressive complex 2 via an H3K27M-like mechanism

Year: 2019

Type: article

Abstract: as the potential interlocutor between DNA methylation and PRC2 activity. We raise the possibility that similar regulatory mechanisms could exist for other methyltransferase complexes such as Trithorax/COMPASS.

Source: Science Advances

DOI: 10.1126/sciadv.aax2887

Authors: Andrea Piunti, Edwin R. Smith, Marc A. J. Morgan, Michal Ugarenko, Natalia Khaltyan, Kathryn A. Helmin, Caila A. Ryan, David C. Murray, Ryan A. Rickels, Bahar D. Yilmaz, Emily J. Rendleman, Jeffrey N. Savas, Benjamin D. Singer, Serdar E. Bulun, Ali Shilatifard

Institution: Northwestern University

Language: English

Topic: Epigenetics and DNA Methylation

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $4,500

Funders: National Institutes of Health, National Heart, Lung, and Blood Institute, National Cancer Institute, National Institute on Deafness and Other Communication Disorders, Eunice Kennedy Shriver National Institute of Child Health and Human Development

Awards: G1645433451, G2534714734, G2934954685, Proteome Biology of Noise Induced Hearing Loss, G6436760769, G9000100825, G9000197324, G9000203232, G9000279980, G9000283955

OpenAlex ID: W2954090867

FWCI: 4.729

Cites: 53

Cited by: 109

Related to: 10