Work

A Pd(II)‐Functionalized Covalent Organic Framework for Catalytic Conjugate Additions of Arylboronic Acids to β,β‐Disubstituted Enones

Year: 2019

Type: article

Abstract: A palladium(II)‐functionalized covalent organic framework (Pd@TpBpy COF) constructed from 1,3,5‐triformylphloroglucinol (Tp) and [2,2′‐bipyridine]‐5,5′‐diamine (Bpy) is reported as a recyclable catalyst for conjugate additions in aqueous media. Additions of an array of stereoelectronically diverse arylboronic acid nucleophiles to β,β‐disubstituted enones form a variety of ketones containing benzylic all‐carbon quaternary centers in up to 92 % isolated yield. Studies on the recyclability of Pd@TpBpy COF show this catalyst remains active through at least 7 cycles and shows superior stability to related MOF catalysts with bipyridine linker units.

Source: ChemCatChem

DOI: 10.1002/cctc.201900894

Authors: Patrick M. Heintz, Brian P. Schumacher, Minda Chen, Wenyu Huang, Levi M. Stanley

Institutions: Iowa State University, Ames National Laboratory

Language: English

Topic: Covalent Organic Framework Applications

Subfield: Materials Chemistry

Field: Materials Science

Domain: Physical Sciences

Open Access status: green

Funders: U.S. Department of Energy, Iowa State University, Ames Laboratory

Awards: G1418315740, G1519358529, G249831736, G524707868, G969889393