Work

Human 5′ UTR design and variant effect prediction from a massively parallel translation assay

Year: 2019

Type: article

Source: Nature Biotechnology

DOI: 10.1038/s41587-019-0164-5

Authors: Paul J. Sample, Ban Wang, David W. Reid, Vlad Presnyak, Iain J. McFadyen, David R. Morris, Georg Seelig

Institutions: University of Washington, Moderna Therapeutics (United States)

Language: English

Topic: RNA and protein synthesis mechanisms

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: U.S. Department of Health and Human Services, Moderna, National Institutes of Health, National Human Genome Research Institute, National Cancer Institute

Awards: RNA circuits for cell state determination in mammalian cells in vitro and in vivo, G4886447427, A predictive model of mRNA stability and translation for variant interpretation and mRNA therapeutics

OpenAlex ID: W2955231772

FWCI: 8.476

Cites: 53

Cited by: 442

Related to: 10