Work

Tuning the chromatin landscape of embryonic stem cells

Year: 2019

Type: article

Abstract: During implantation, cells of the embryo dramatically increase their proliferation rate. This developmental transition involves increased demand for the synthesis of building blocks needed to support the growth of post-implantation epiblast cells. Embryonic stem cells (ESCs) cultured in serum closely resemble cells of the post-implantation epiblast and similarly exhibit high proliferation rates (1).

Source: Stem Cell Investigation

DOI: 10.21037/sci.2019.06.02

Author: Diana C. Hargreaves

Institution: Salk Institute for Biological Studies

Language: English

Topic: Pluripotent Stem Cells Research

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: diamond

Funders: National Institute of General Medical Sciences, National Institute of Allergy and Infectious Diseases

Awards: The role of BAF related complexes in regulatory T cell development and function, G8104856122