Work

Pearls & Oy-sters: Adolescent-onset adrenomyeloneuropathy and arrested cerebral adrenoleukodystrophy

Year: 2019

Type: article

Abstract: Defects in peroxisomal transport interferes with β-oxidation of very long chain fatty acids (VLCFAs). Subsequent VLCFA accumulation triggers a cascade of events that eventually leads to adrenoleukodystrophy (ALD).

Source: Neurology

DOI: 10.1212/wnl.0000000000007755

Authors: Jieru E. Lin, Eric A. Armour, Arezou Heshmati, Christine Umandap, Julia J. Couto, Alejandro D. Iglesias, Eric J. Mallack, Jennifer M. Bain

Institutions: NewYork–Presbyterian Hospital, Columbia University Irving Medical Center, University of Illinois Chicago, Weill Cornell Medicine, Columbia University

Language: English

Topic: Metabolism and Genetic Disorders

Subfield: Clinical Biochemistry

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: National Institutes of Health, National Institute of Neurological Disorders and Stroke

Awards: WCMC Child Neurology Postdoctoral Training in Developmental Neurosciences, G7988125268

OpenAlex ID: W2956732148

FWCI: 1.21

Cites: 11

Cited by: 10

Related to: 10