Work

Development of Opsonic Mouse Monoclonal Antibodies against Multidrug-Resistant Enterococci

Year: 2019

Type: article

Abstract: strains. The sequences from the variable regions of the heavy and light chains were reconstructed in expression vectors, and the activity of the MAbs upon expression in eukaryotic cells was confirmed with the same immunological assays. In summary, we identified two opsonic MAbs against enterococci which could be used for therapeutic or prophylactic approaches against enterococcal infections.

Source: Infection and Immunity

DOI: 10.1128/iai.00276-19

Authors: Ermioni Kalfopoulou, Diana Laverde, Karmela Miklic, Felipe Romero-Saavedra, Suzana Malic, Filippo Carboni, Roberto Adamo, Tihana Lenac Rovis, Stipan Jonjic, Johannes Huebner

Institutions: Ludwig-Maximilians-Universität München, University of Rijeka, GlaxoSmithKline (Italy)

Language: English

Topic: Monoclonal and Polyclonal Antibodies Research

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funder: European Commission

Award: A training network for the rational design of the next generation of well-defined glycoconjugate vaccines

OpenAlex ID: W2957105212

FWCI: 0.33

Cites: 57

Cited by: 11

Related to: 10