Преждевременное адренархе: этиология и клиническое значение
Year: 2017
Type: article
Abstract: Adrenarche is a zona reticularis maturation process accompanied by intensification of androgen production. Premature adrenarche is defined by onset of pubic and underarm hair, greasiness of skin and hair, «mature» sweaty odor against the increase of adrenal androgens level in girls aged up to 8 years and in boys aged up to 9 years. Presented in this article are contemporary data on etiology, pathogenesis, and clinical significance of premature adrenarche. The high risk of development of insulin resistance, polycystic ovarian syndrome and hyperandrogenism necessitates studying the etiology of premature adrenarche further with the aim of identifying risk groups in relation to formation of metabolic complications.
Authors: Н. В. Волкова, А. В. Солнцева
Institution: Belarusian State Medical University
Language: Russian
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2959859334