Work

Measurement of T1 and T2 relaxation times of the pancreas at 7 T using a multi-transmit system

Year: 2019

Type: article

Abstract: To determine T 1 and T 2 relaxation times of healthy pancreas parenchyma at 7 T using a multi-transmit system. Twenty-six healthy subjects were scanned with a 7 T MR system using eight parallel transceiver antennas, each with two additional receive loops. A Look-Locker sequence was used to obtain images for T 1 determination, while T 2 was obtained from spin-echo images and magnetic resonance spectroscopy measurements with different echo times. T 1 and T 2 times were calculated using a mono-exponential fit of the average magnitude signal from a region of interest in the pancreas and were tested for correlation with age. The age range of the included subjects was 21–72 years. Average T 1 and T 2 relaxation times in healthy pancreas were 896 ± 149 ms, and 26.7 ± 5.3 ms, respectively. No correlation with age was found. T 1 and T 2 relaxation times of the healthy pancreas were reported for 7 T, which can be used for image acquisition optimization. No significant correlations were found between age and T 1 or T 2 relaxation times of the pancreas. Considering their low standard deviation and no observable age dependence, these values may be used as a baseline to study potentially pancreatic tissue affected by disease.

Source: Magnetic Resonance Materials in Physics Biology and Medicine

DOI: 10.1007/s10334-019-00768-w

Authors: Mariska Damen, Maarten van Leeuwen, Andrew Webb, Dennis Klomp, Catalina Arteaga de Castro

Institutions: Leiden University Medical Center, University Medical Center Utrecht

Language: English

Topic: Advanced MRI Techniques and Applications

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,140