Work

LKB1 specifies neural crest cell fates through pyruvate-alanine cycling

Year: 2019

Type: article

Abstract: mutant mice. These data uncover a link between pyruvate-alanine cycling and the specification of glial cell fate with potential implications in the understanding of the molecular pathogenesis of neural crest diseases.

Source: Science Advances

DOI: 10.1126/sciadv.aau5106

Authors: Anca G. Radu, Sakina Torch, Florence Fauvelle, Karin Pernet-Gallay, Anthony Lucas, Renaud Blervaque, Véronique Delmas, Uwe Schlattner, Laurence Lafanechère, Pierre Hainaut, Nicolas Tricaud, Véronique Pingault, Nadège Bondurand, Nabeel Bardeesy, Lionel Larue, Chantal Thibert, Marc Billaud

Institutions: Centre National de la Recherche Scientifique, Inserm, Institut pour l'avancée des biosciences, Université Grenoble Alpes, Grenoble Institute of Neurosciences, IRMaGe, La Ligue Contre le Cancer, Institut Curie, Laboratory of Fundamental and Applied Bioenergetics, Université de Montpellier, Institute for Neurosciences of Montpellier, Institut des Maladies Génétiques Imagine, Harvard University, Massachusetts General Hospital, Lyon 1 Université, Centre Léon Bérard, Centre de Recherche en Cancérologie de Lyon

Language: English

Topic: Developmental Biology and Gene Regulation

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $4,500

Funders: Association pour la Recherche sur le Cancer, Ligue Contre le Cancer, Institut National Du Cancer, National Institutes of Health, National Cancer Institute

Awards: G5895427028, G7822442412

OpenAlex ID: W2960857704

FWCI: 0.827

Cites: 81

Cited by: 22

Related to: 10