Consensus criteria for diagnosis, staging, and treatment response assessment of T-cell prolymphocytic leukemia
Year: 2019
Type: article
Abstract: T-cell prolymphocytic leukemia (T-PLL) is a rare, mature T-cell neoplasm with a heterogeneous clinical course. With the advent of novel treatment options that will potentially change the management of patients with T-PLL, it has become necessary to produce consensus guidelines for the design and conduct of clinical trials. The T-PLL International Study group (TPLL-ISG) set out to define standardized criteria for diagnosis, treatment indication, and evaluation of response. These criteria will facilitate comparison of results from clinical trials in T-PLL, and will thus support clinical decision making, as well as the approval of new therapeutics by healthcare authorities.
Source: Blood
Authors: Philipp B. Staber, Marco Herling, Mar Bellido, Eric D. Jacobsen, Matthew S. Davids, Tapan Mahendra Kadia, Andrei Shustov, Olivier Tournilhac, Emmanuel Bachy, Francesco Zaja, Kimmo Porkka, Gregor Hoermann, Ingrid Simonitsch-Klupp, Claudia Haferlach, Stefan Kubicek, Marius E. Mayerhoefer, Georg Hopfinger, Ulrich Jaeger, Claire Dearden
Institutions: Medical University of Vienna, University of Cologne, Cologne Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases, University Medical Center Groningen, University of Groningen, Dana-Farber Cancer Institute, The University of Texas MD Anderson Cancer Center, Seattle Cancer Care Alliance, University of Washington, Centre Hospitalier Universitaire de Clermont-Ferrand, Hospices Civils de Lyon, Azienda Sanitaria Universitaria Integrata di Trieste, Helsinki University Hospital, Innsbruck Medical University, University Hospital Innsbruck, Munich Leukemia Laboratory (Germany), Austrian Academy of Sciences, CeMM Research Center for Molecular Medicine, Memorial Sloan Kettering Cancer Center, Royal Marsden NHS Foundation Trust, Royal Marsden Hospital
Language: English
Subfield: Genetics (clinical)
Field: Medicine
Domain: Health Sciences
Open Access status: green
Funder: National Cancer Institute
Award: Cancer Center Support Grant
OpenAlex ID: W2961584900