Work

Stereotactic radiation therapy combined with immunotherapy: augmenting the role of radiation in local and systemic treatment.

Year: 2015

Type: article

Abstract: Stereotactic radiosurgery and stereotactic body radiation therapy are two contemporary radiation modalities that can treat tumors in any area of the body using highly focused radiation. Recently, immunotherapy has established itself as a viable and powerful anticancer treatment. In this review we detail the rationale supporting a combination of immunotherapy and stereotactic radiation. Additionally, we discuss the evidence for the immune stimulatory effects of focused radiation and the role that radiation may play in enhancing the systemic treatment effects of immunotherapy.

Source: PubMed

Authors: Andrew B Sharabi, Phuoc T Tran, Michael Lim, Charles G Drake, Theodore L Deweese

Language: English

Topic: Cancer Immunotherapy and Biomarkers

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Institutes of Health

Award: Structure-Functions Studies of Twist1-induced Radioresistance in Lung Cancer

OpenAlex ID: W296314837

FWCI: 4.942

Cites: 83

Cited by: 72

Related to: 10