Not All Home-based Exercise Programs Are Home-based Pulmonary Rehabilitation Programs
Year: 2019
Type: letter
Abstract: To further put these changes into clinical context, we previously measured IOS in response to propranolol-induced bronchoconstriction in patients with asthma where there was a 0.05 (kPa/L) $ s increase in R5 2 R20 corresponding to a 104.1% (95% CI, 22.6 to 185.6%) change, along with a subsequent bronchodilator response to salbutamol of 20.17 (kPa/L) $ s and 2115.6%(95% CI, 255.6% to 2175.7%), respectively (2).Moreover, in a health informatics evaluation of 302 patients with asthma, there was a 45% increased risk for worse control in relation to oral corticosteroid use, and 47% in relation to inhaled albuterol use measured during a 2-year period when comparing cohorts of patients with asthma, using a cutoff value for R5 2 R20 of less than or greater than 0.07 (kPa/L) $ s (3).Hence, the small airway asthma phenotype reflected by abnormal R5 2 R20 is associated with poorer control.We believe the findings of Foy and colleagues (1) are important in further validating the use of IOS in determining effects of treatments on small airways of patients with asthma.
Author: Marilyn L. Moy
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W2963371730