Work

Development of nuclear magnetic resonance as a tool of quantitative analysis for organic materials

Year: 2019

Type: article

Abstract: It has been recognized for a long time that nuclear magnetic resonance (NMR) spectroscopy can be used for quantification; the resonance peak area is known to be proportional to the number of nuclei contributing to the peak. However, quantification by Fourier transformation (FT) NMR was believed to be only accurate to within a few percent to 10%, and in general, analytical chemists thought the level of accuracy was not satisfactory. However, about 20 years ago, chemical metrologists began to recognize the usefulness of quantitative applications of NMR for determining the purity of organic materials. Here, we present a brief review on purity assessment of the quantitative NMR (qNMR) and its contribution to the consultative committee for amount of substance: metrology in chemistry and biology (CCQM) working group on organic analysis (OAWG).

Source: Metrologia

DOI: 10.1088/1681-7575/ab348d

Authors: Takeshi Saito, Taichi Yamazaki, Masahiko Numata

Institutions: National Metrology Institute of Japan, National Institute of Advanced Industrial Science and Technology

Language: English

Topic: Scientific Measurement and Uncertainty Evaluation

Subfield: Statistics, Probability and Uncertainty

Field: Decision Sciences

Domain: Social Sciences

Open Access status: bronze

OpenAlex ID: W2963523166

FWCI: 0.839

Cites: 50

Cited by: 19

Related to: 10