Year: 2019
Type: article
Abstract: Gamma-aminobutyric acid (Gaba) is a non-proteinogenic amino acid that is widely present in microorganisms, plants, and vertebrates. So far, Gaba is well known as a main inhibitory neurotransmitter in the central nervous system. Its physiological roles are related to the modulation of synaptic transmission, the promotion of neuronal development and relaxation, and the prevention of sleeplessness and depression. Besides, various pharmaceutical properties of Gaba on non-neuronal peripheral tissues and organs were also reported due to anti-hypertension, anti-diabetes, anti-cancer, antioxidant, anti-inflammation, anti-microbial, anti-allergy, hepato-protection, reno-protection, and intestinal protection. Therefore, Gaba may be considered as potential alternative therapeutics for prevention and treatment of various diseases. Accordingly, this updated review was mainly focused to describe the pharmaceutical properties of Gaba as well as emphasize its important role regarding human health.
Source: Molecules
Authors: Dai-Hung Ngo, Thanh Sang Vo
Institutions: Thu Dau Mot University, Trường ĐH Nguyễn Tất Thành
Language: English
Topic: GABA and Rice Research
Subfield: Plant Science
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $1,824
OpenAlex ID: W2964193653