Year: 2019
Type: article
Abstract: GATA-3 regulates the differentiation, proliferation, survival, and function of peripheral T cells and their thymic progenitors. Recent findings, reviewed here, not only implicate GATA-3 in the pathogenesis of molecularly, genetically, and clinically distinct T-cell lymphoproliferative disorders, but also have significant diagnostic, prognostic, and therapeutic implications.
Source: IUBMB Life
DOI: 10.1002/iub.2130
Authors: Carlos Murga‐Zamalloa, Ryan A. Wilcox
Institutions: University of Michigan, Michigan Medicine
Language: English
Subfield: Pathology and Forensic Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
Funder: National Cancer Institute
Awards: G247166205, G537029356
OpenAlex ID: W2964333394