Work

Titrating gene expression using libraries of systematically attenuated CRISPR guide RNAs

Year: 2020

Type: article

Source: Nature Biotechnology

DOI: 10.1038/s41587-019-0387-5

Authors: Marco Jost, Daniel A. Santos, Reuben A. Saunders, Max A. Horlbeck, John S. Hawkins, Sonia M. Scaria, Thomas M. Norman, Jeffrey A. Hussmann, Christina R. Liem, Carol A. Gross, Jonathan S. Weissman

Institutions: QB3, Howard Hughes Medical Institute, University of California, San Francisco, Memorial Sloan Kettering Cancer Center

Language: English

Topic: CRISPR and Genetic Engineering

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funders: Howard Hughes Medical Institute, University of California, San Francisco, National Human Genome Research Institute, National Cancer Institute, National Institute of General Medical Sciences

Awards: G1150296444, G1967503053, Systematic Genome-Wide Characterization of Iron Homeostasis, Medical Scientist Training Program, The Cancer Target Discovery and Development Network at UCSF, G5052434461, G896813969

OpenAlex ID: W3000149627

FWCI: 7.131

Cites: 56

Cited by: 164

Related to: 10