Year: 2019
Type: article
Abstract: Ehlers-Danlos Syndrome is a genetic connective tissue disease with varying expressions and phenotypes. Hypermobile Ehlers-Danlos Syndrome (hEDS) is the most prevalent subgroup within this disease category. It is estimated to make up about 80% of the total population of those with EDS (Tinkle et al., 2017). New and updated diagnostic criteria was established in 2017 for hEDS as a way to categorize the syndrome apart from other connective tissue diseases on the hypermobility spectrum of diseases. The disease expressive itself through a complex pathological process and in varying degrees and levels of severity for those who inherit it (Castori et al., 2017). Disease management is specific to the body system involved and successful treatment utilizes a multi-system, multidisciplinary approach beginning as early as childhood to decrease disease burden across the lifespan (Scheper, Nicholson, Adams, Tofts, & Pacey, 2017).
Author: Jocelyn Akers
Language: English
Subfield: Genetics
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W2966190465