Work

Gene expression of TMEM178, which encodes a negative regulator of NFATc1, decreases with the progression of asthma severity

Year: 2019

Type: article

Abstract: In two independent microarray studies involving primary airway epithelial cells, the relative gene expression of TMEM178 decreases with the progression of asthma severity. Our manuscript creates a paradigm for future studies dissecting the role of Tmem178 in the pathogenesis of severe asthma.

Source: Clinical and Translational Allergy

DOI: 10.1186/s13601-019-0280-9

Authors: Naiya B. Patel, Lorena A. Ostilla, Lyda Cuervo-Pardo, Sergejs Berdnikovs, Sergio E. Chiarella

Institutions: Northwestern University, University of Florida

Language: English

Topic: Asthma and respiratory diseases

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,300