Effect of moxibustion at Shenque (CV 8) on cardiac remodeling and myocardial function in rats with exercise-induced fatigue
Year: 2019
Type: article
Abstract: Exercise-induced arrhythmia affects the stamina, health, regular training, and competition of athletes，and that is related to pathological changes in the structure of the myocardium caused by long-term and repeated high-intensity exercise. Previous experiments have confirmed that moxibustion at Shenque (CV 8) regulates myocardial oxygen free radical production and the antioxidant capacity in rats with exercise-induced fatigue, and reduces myocardial damage. However, the effect on Cardiac Remodeling and Myocardial Function are still unclear. This study will evaluate the therapeutic efficacy of moxibustion at Shenque (CV 8) on myocardial structure and function in a model of exercise-induced fatigue by measuring serum myoglobin (Mb), creatine kinase-muscle/brain (CK-MB), and cardiac troponin-I (cTnI) levels, left ventricular end diastolic diameter (LVEDd), left ventricular end systolic diameter (LVESd), left ventricular fractional shortening (LVFS), ejection fraction (EF), peak early diastolic mitral blood flow velocity (E), and peak late diastolic mitral blood flow velocity (A). Our results moxibustion at Shenque (CV 8) effectively prevents structural changes in the heart caused by exercise-induced fatigue and enhances heart function. This treatment does not exert side effects on healthy rats and is a safe and effective technique.
Source: Biocell
Institution: Hebei University of Chinese Medicine
Language: English
Subfield: Complementary and alternative medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W2966529758