Work

Long noncoding RNA CRNDE activates Wnt/β-catenin signaling pathway through acting as a molecular sponge of microRNA-136 in human breast cancer.

Year: 2017

Type: article

Abstract: assay showed that the average tumor volume and weight were largest in the group of CRNDE overexpression. CRNDE might hyperactivate the Wnt/β-catenin signaling pathway through directly repressing miR-136 expression in BC; CRNDE could be considered as a prognostic biomarker and therapeutic target in BC diagnosis and treatment.

Source: PubMed Central

Authors: Jinliang Huan, Li Xing, Qianhuang Lin, Hu Xui, Xianju Qin

Institution: Shanghai Eighth People Hospital

Language: English

Topic: Cancer-related molecular mechanisms research

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2966564411

FWCI: 5.325

Cites: 40

Cited by: 83

Related to: 10