Work

First High-Resolution Crystal Structures of the Glucocorticoid Receptor Ligand-Binding Domain–Peroxisome Proliferator-Activated γ Coactivator 1-α Complex with Endogenous and Synthetic Glucocorticoids

Year: 2019

Type: article

Source: Molecular Pharmacology

DOI: 10.1124/mol.119.116806

Authors: Xu Liu, Yashuo Wang, Eric A. Ortlund

Institutions: Qingdao University, Emory University

Language: English

Topic: Estrogen and related hormone effects

Subfield: Endocrinology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: U.S. Department of Energy, American Heart Association, Emory University, Office of Science, School of Medicine, Emory University, National Institute of Diabetes and Digestive and Kidney Diseases, Basic Energy Sciences, Argonne National Laboratory

Awards: Structure-function of tafazzin in cardiac muscle wasting, G1678787968, G1756342139, G18202666, G2123841078, G572720644, Targeting the orphan nuclear receptor LRH-1 with small molecules

OpenAlex ID: W2966848316

FWCI: 2.265

Cites: 53

Cited by: 32

Related to: 10